Significance of Interferon-γ in Coronary Artery Bypass Surgery

نویسندگان

  • Sadir J. Alrawi
  • Azza A. Abo Deeb
  • Mohammed Samee
  • Ramanathan Raju
  • Djamshid Shirazian
  • Anthonay J. Acinapura
  • Joseph N. Cunningham
چکیده

BACKGROUND Gamma interferon (IFN-gamma) is produced by activated natural killer and T cells under pathologic circumstances. The objective of our study was to compare the level of IFN-gamma in open and endoscopic methods of vein harvesting for coronary artery bypass surgery (CABG). METHOD Ninety samples of human saphenous veins harvested from patients prepared for CABG. Pre- and post-procedure sera of the patients, in addition to supernatants of 3-day endothelial cell culture, were analyzed for IFN-gamma. RESULTS The mean preoperative IFN-gamma level (0.09+/-0.03 pg/mL) and that for postoperative sera (0.08+/-0.02 pg/mL) were not significantly different (P = 0.2). The mean IFN-gamma level in endothelial cell culture from the endoscopic (0.18+/-0.21 pg/mL) and the open method (0.19+/-0.39 pg/mL) were not significant (P = 0.89). CONCLUSION We recommend the endoscopic method of vein harvesting because of its lower morbidity and earlier hospital discharge.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of coronary artery bypass on QT dispersion

Introduction: QT dispersion (QT Max – QT min) reflects inhomogeneous ventricular depolarization that may provide a substrate for serious arrythmias and is associated with adverse clinical outcomes in patients with coronary artery disease. Some studies have shown reduction in QT dispersion after successful angioplasty due to coronary reperfusion, but effect of coronary artery bypass grafting o...

متن کامل

The prevalence of wound infection in patients undergoing coronary artery bypass graft surgery in a hospital in Mashhad city from 2009-2011

Introduction: Postoperative wound infection is a complication that occurs after coronary artery bypass graft surgery. The aim of this study was to examine the incidence of wound infections after coronary artery bypass graft surgery among the patients operated in Ghaem Hospital in the city of Mashhad from 2009-2011. Methods: This cross-sectional study was performed in the years 2009 to 2011 o...

متن کامل

Effects of Seasonal Variations on the Outcome of Coronary Artery Bypass Graft Surgery

Background: For all the reports on the association between seasons and coronary artery disease, there is a paucity of information on the possible effects of seasonal variations on the outcome of patients after coronary artery bypass grafting surgery (CABG). The aim of this study was to assess the short-term outcome of post-CABG patients in the four different seasons to find any correlation betw...

متن کامل

The factors that affect blood and blood products usage in coronary artery graft surgery

Background: Coronary artery bypass surgery is one of the surgeries in which high blood transfusions are needed. About 20% of all surgical operations require a blood transfusion. Packed cell administration increases perioperative morbidity and mortality. In the United States, from every 1000 people, one has undergone a coronary artery bypass graft surgery, and it is estimated that around 800,000...

متن کامل

Coronary Artery Disease Risk Factors in Patients Undergoing Coronary Artery Bypass Graft Surgery

Introduction: Nowadays, with the advancement of technology and industrial life, the prevalence of heart diseases including coronary artery diseases has considerably increased. Coronary artery diseases are one of the most common and serious diseases that threaten human life. Methods: The present study is a comparative-descriptive research. The statistical ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2001